A Virtual Reality View: Individualizing the Management of Relapsed and/or Refractory Multiple Myeloma: Novel Combination Treatment Options and Sequencing Strategies
6:00 PM – 8:00 PM
JW Marriott Miami
1109 Brickell Avenue
Miami, FL 33131
Meeting room: Salons E & F & G
Thursday, May 2, 2019
6:00 PM Eastern 5:00 PM Central 4:00 PM Mountain 3:00 PM Pacific
- Virtual Reality animations
- iPads provided to enhance learning experience
- Personalized posters
Ajay K. Nooka, MD, MPH, FACP
Division of Bone Marrow Transplant
Winship Cancer Institute
Emory University School of Medicine
Ajai Chari, MD
Associate Professor of Medicine
Hematology & Medical Oncology
Icahn School of Medicine at Mount Sinai
New York, NY
I. Multiple myeloma (MM): an overview
i. Role of age
ii. Role of ethnicity
b. Disease pathophysiology
c. Disease course: relapsed/refractory (R/R)
d. Disease burden/effects on patient quality of life
II. Individualizing the sequencing of care for patients with R/R MM
a. Disease-related considerations
i. Nature of relapse (indolent vs aggressive)
ii. Risk stratification
iii. Genetics of initial and relapsed marrow
iv. Disease burden (high vs low)
v. Revised International Staging System (R-ISS) staging for MM (1 vs 2–3)
b. Treatment-related factors
i. Previous therapy
ii. Regimen-related toxicity
iii. Depth and duration of previous response, tumor burden at relapse
c. Patient-related factors
i. Renal insufficiency
ii. Hepatic impairment
iii. Comorbidities and frailty
iv. Patient preferences
III. Novel therapeutic options for the treatment of R/R MM
a. Recently-approved next-generation PIs and IMiDs
b. MOAs and clinical trial efficacy and safety data for mAbs
c. (VR Theme: MOA of elotuzumab)
d. NCCN guideline recommendations
i. Recommendations that include mAbs
ii. (VR Theme: MOA of NCCN guideline "preferred" regimen recommendation [elotuzumab/lenalidomide/dexamethasone] and "other suggested" regimen recommendation [elotuzumab/bortezomib/dexamethasone])
IV. The role of physician-patient communication in R/R MM
a. Evidence suggesting physician-patient communication barriers
b. Strategies to improve physician-patient interactions
V. Case studies
VII. Questions and answers
After completing the educational activity, learners should be better able to:
- Describe the MOAs and clinical profiles of novel treatment options for patients with R/R MM
- Individualize the selection and sequencing of novel drug combination therapies through multiple remissions and subsequent relapses based on disease-, treatment-, and patient-related factors
- Apply strategies that will improve communication, engagement, education, and decision making with patients with R/R MM and their health care providers
This initiative is designed to meet the educational needs of community and academic medical oncologists and advanced practitioners (NP/PA/PharmD) involved in the management of patients with MM.
Med Learning Group is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.
CREDIT DESIGNATION STATEMENT
Med Learning Group designates this live activity for a maximum of 2.0 AMA Category 1 Credit(s)TM. Physicians should claim only the credit commensurate with the extent of their participation in the live activity.
NURSING CREDIT INFORMATION
Purpose: This program would be beneficial for nurses involved in the care of patients with multiple myeloma.
Credits: 2.0 ANCC Contact Hours
CNE Accreditation Statement: Ultimate Medical Academy/CCM is accredited as a provider of continuing nursing education by the American Nurses Credentialing Center’s Commission on Accreditation. Awarded 2.0 contact hours of continuing nursing education of RNs and APNs
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